Not really. Anyone prone to motion sickness in general is likely to get it when doing VR, and some people who never get motion sick still get it when playing VR. Varies on the game you play too.
Personally, I usually don't get motion sick, but when I first got my Index and played HL: Alyx, the game kept bugging out on me and made me really sick. Also if the lenses aren't adjusted properly it probably increases chance of getting motion sickness and headaches, like wearing wrong prescription glasses.