Assuming you mean 'Losing', then Azarinth Healer.
There's a couple others, but it's usually a big deal, something that happens late in the story. It would be pretty big spoilers, and I'm not sure why you're looking for this type of story.
You could try these....
There would be "a journey in darkness" where it's a bigger deal. Though, I personally had issues with themdescription of how she still could deal with daily life and use tools.