I really don't understand why people like Itachi...

[sanitylimited]

That's definitely not canon, but cool theory anyway. I don't believe the Third would do that though. I can see Danzo somehow being involved though. Still doesn't explain the lack of Senju children unless Danzo has his Root guys killing the orphans after killing their parents.

if iwaki (tsunades brother) can die than all of them can die.
they probably prioratized the kids for the hashirama cells experiments.

ether way the third hokage over relied on propaganda to maintain control, leaving their military extremely weak. and he wasnt even controlled by zetsu like every other village.

 

[Lloyd]

Itachi has something I like to call X factor.

 

[phaeous]

Well... Uchiha are really interesting, why exterminate them?

No matter what genes you are born with, free will lets you exert your own nature.

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Senju?

Hashirama had all but the main line forgo their surname and blend into the village individually.

Danzo's wood gekkai genkai experiment plucked them out and murdered them.

Tsunade became infertile after losing too much vitality in battle.